The GPU water cooling is the second most popular choice for the custom liquid cooling project after central processor cooling. It is also can be the most tricky one. While many video cards have the same circuit board layout across all manufacturers (reference design), some models may have multiple variations, also known as custom boards, such as Strix, Windforce, etc.  Your very first step in GPU water cooling project must be verification that there is a product that fits your card model. Use online tools like EKWB watercooling configurator to determine compatibility between blocks and your GPU.